Preclinical pharmacology of azd9977: a novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion

HIGHLIGHTS

• who: Krister Bamberg and colleagues from the Team, Paris, France, Division of Nephrology and Hypertension, Department of Internal Medicine, University have published the research work: Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0193380]. February 23, 2018 of /1371/
• what: Based on the final population pharmacokinetic model, the eight hour study window was simulated and mean exposure was retrieved from these simulations.
• how: This study was carried out in strict accordance with . . .
  

   

  

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