Preclinical reserpine models recapitulating motor and non-motor features of parkinson s disease: roles of epigenetic upregulation of alpha-synuclein and autophagy impairment

HIGHLIGHTS

  • who: October and collaborators from the France Federal University of Santa Catarina have published the Article: Preclinical reserpine models recapitulating motor and non-motor features of Parkinson s disease: Roles of epigenetic upregulation of alpha-synuclein and autophagy impairment, in the Journal: (JOURNAL)
  • what: The authors aimed to develop preclinical animal models of reserpine-induced PD showing motor and non-motor symptoms, and to identify the molecular and cellular mechanisms underlying the effects of reserpine in_vivo and in_vitro. PD is one of the main reasons for disability globally, and its incidence is increasing at a . . .

     

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