Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors

HIGHLIGHTS

• who: Marie Morfouace from the Department of Pharmaceutical Sciences, StJude Children’s, USA CR UK Cambridge Institute, Li Ka Shing Centre, University have published the research work: Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors, in the Journal: (JOURNAL)
• what: The authors propose to implement the preclinical screening pipeline as a standard of practice.
• how: As an example of the pipeline data are presented for the combination of 5-fluoro-20 -deoxycytidine and tetrahydrouridine in three pediatric brain tumor models. To better select and assess potential new therapies . . .
  

   

  

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