Preclinical toxicity and immunogenicity of a covid-19 vaccine (zf2001) in cynomolgus monkeys

HIGHLIGHTS

• who: Hongzhong Yang and collaborators from the Center of Safety Evaluation and Research, Hangzhou Medical College, Hangzhou, China have published the research: Preclinical Toxicity and Immunogenicity of a COVID-19 Vaccine (ZF2001) in Cynomolgus Monkeys, in the Journal: Vaccines 2022, 2080 of /2022/
• what: A flowchart of this study is presented in Figure 2. Although the authors did not detect serum Th1/Th2 type cytokine profiling, which will be helpful to reduce security concerns about ADE or VED, the immunotoxicity and systemic toxicity results in this study shows no abnormal changes, including white cells, IgG . . .
  

   

  

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