Preclinical toxicological assessment of levothyroxine and liothyronine maillard impurities

HIGHLIGHTS

  • who: Advance access publication date et al. from the (UNIVERSITY) have published the article: Preclinical toxicological assessment of levothyroxine and liothyronine Maillard impurities, in the Journal: (JOURNAL)
  • what: No concerns regarding the toxicity, carcinogenicity, or mutagenicity of LeMI and LiMI have been raised in either of the nonclinical tests performed.
  • how: The studies were designed to use the minimum number of animals possible. Homogeneous data were compared using analysis of variance in case of statistical significance pairwise comparisons of each treated group with the control group were made In silico toxicological assessment Leadscope . . .

     

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