HIGHLIGHTS
SUMMARY
In fact, a recent study showed that relatively high Aβ levels even in the subthreshold at baseline predicted memory decline and conversion to Aβ (+) status in a subset of Aβ individuals. Recent findings revealed a focal Aβ elevation in specific brain regions of the Aβ individuals who subsequently converted to Aβ (+) status. The authors used an artificial neural_network (ANN) model that considered different combinations of features to predict the conversion from Aβ to Aβ (+). External validation with the model using demographic features and global SUVR showed excellent performance (AUROC=0.900), which means that . . .
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