Predicting egg passage adaptations to design better vaccines for the h3n2 influenza virus

HIGHLIGHTS

• who: Yunsong Liu and colleagues from the Beijing, China University of the Chinese Academy of, Beijing, China have published the research work: Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus, in the Journal: Viruses 2022, 2065 of 15/09/2020
• what: To capture the egg passage mutations, the authors focused on substitutions along the terminal branches of the egg sequences .
• how: Leveraging the unique fitness landscape the authors developed a novel machine learning model that can predict egg passage substitutions for any candidate vaccine strain before the passage . . .
  

   

  

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