Predicting kinase inhibitors using bioactivity matrix derived informer sets

HIGHLIGHTS

  • who: Huikun Zhang and collaborators from the Department of Statistics, University of Wisconsin-Madison, Madison, Wisconsin, United States of have published the research work: Predicting kinase inhibitors using bioactivity matrix derived informer sets, in the Journal: (JOURNAL)
  • what: The authors compare different ways of using chemogenomic to choose a small informer set of compounds based on previously measured bioactivity The authors develop this Informer-Based-Ranking (IBR) approach using the Published Kinase Inhibitor Sets (PKIS) as the chemogenomic to select the informer sets. The authors test the informer compounds on a target that is not . . .

     

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