Predicting protein function and orientation on a gold nanoparticle surface using a residue-based affinity scale

HIGHLIGHTS

  • who: Joanna Xiuzhu Xu from the Department of Chemistry, Mississippi State University, Mississippi State, MS, USA have published the research work: Predicting protein function and orientation on a gold nanoparticle surface using a residue-based affinity scale, in the Journal: (JOURNAL) of 21/03/2022
  • what: This approach has been calibrated to citrateAuNP surfaces and will likely not be applicable to other nanoparticle surface chemistries.
  • how: This approach may be problematic especially if desorption is slow compared to the measurement timescale nevertheless the observed Kd values often mirror other trends in binding affinity27 . . .

     

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