Prediction models for brain distribution of drugs based on biomimetic chromatographic data

HIGHLIGHTS

• who: Theodosia Vallianatou and colleagues from the Medical Mass Spectrometry Imaging, Department of Pharmaceutical Biosciences, University, Faculty of Pharmacy, National and Kapodistrian University of Athens, , Athens, Greece have published the paper: Prediction Models for Brain Distribution of Drugs Based on Biomimetic Chromatographic Data, in the Journal: Molecules 2022, 27, x FOR PEER REVIEW of /2022/
• what: The authors combined experimental obtained by HPLC using three columns i.e. immobilized artificial membranes human serum albumin and α1 -acid glycoprotein with molecular descriptors to model brain disposition of Kp uu brain as the ratio between the unbound . . .
  

   

  

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