Prediction of prognosis, immunogenicity and efficacy of immunotherapy based on glutamine metabolism in lung adenocarcinoma

HIGHLIGHTS

  • who: Jichang Liu from the Jiaotong, China have published the article: Prediction of prognosis, immunogenicity and efficacy of immunotherapy based on glutamine metabolism in lung adenocarcinoma, in the Journal: (JOURNAL)

SUMMARY

    Recent investigations revealed that oncogenic transformation induces a well-characterized metabolic phenotype in tumor cells, which in turn affects the tumor environment (TME). In this harsh TME, infiltrating immune cells are forced to undergo relevant metabolic adaptations, which in turn disrupt the antitumor effects of immune cells. Therapeutic strategies that target tumor metabolism and thus modulate or improve immune cell metabolism to . . .

     

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