Predictive and concurrent validity of pain sensitivity phenotype, neuropeptidomics and neuroepigenetics in the mi-rat osteoarthritic surgical model in rats

HIGHLIGHTS

• What: In continuation of the previous studies, this work aims to advance the development of quantitative sensory testing (QST) of pain in association with neuropeptidomics and neuroepigenetics. The aim of this study was to pursue the refinement of the MI-RAT model by validating a panel of pain assessment methods, including functional neuropeptidomics, neuroepigenetics, and innovative QST applied to the experimental MI-RAT model, to characterize OA pain with great validity and reliability.
• Who: Asuncion Romero-Molina and collaborators from the Zhejiang Provincial People`s Hospital, China University of Algarve, Portugal have published the research . . .
  

   

  

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