HIGHLIGHTS
SUMMARY
Identifying an instrument or marker that can anticipate the diagnosis of acute appendicitis and may differentiate uncomplicated and complicated appendicitis with acceptable sensitivity and specificity is, up to this day, an object of concern among researchers. Numerous scoring systems have been proposed to support the clinician in diagnosing and categorizing acute appendicitis, such as the Alvarado score, pediatric appendicitis score (PAS), the appendicitis inflammatory response (AIR), and Shera score. The accuracy of white blood cells (WBC) and neutrophils for diagnosis of appendicitis differ among articles, as normal leukocyte counts do not exclude appendicitis, and . . .
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