Predominance of brca2 mutation and estrogen receptor positivity in unselected breast cancer with brca1 or brca2 mutation

HIGHLIGHTS

  • who: Pascal Pujol and collaborators from the Department of Cancer Genetics, CHU Montpellier, Universitu00e9 de Montpellier, Montpellier, FranceINSERM, Centre Perrin, Department of BioPathology, University Clermont Auvergne have published the Article: Predominance of BRCA2 Mutation and Estrogen Receptor Positivity in Unselected Breast Cancer with BRCA1 or BRCA2 Mutation, in the Journal: (JOURNAL)
  • what: This study shows that the frequency of gBRCA2 carriage is higher than expected in both unselected breast cancer patients and in the general population.
  • future: Studies on the benefit of PARPi therapy in the adjuvant setting of gBRCA patients are required . . .

     

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