Pregnancy state before the onset of labor: a holistic mechanical perspective

HIGHLIGHTS

• What: Through a series of numerical simulations the authors investigate the mechanical impact of_(i) initial shape (ii) stiffness (iii) and_(iv) intrauterine pressure. In this work, the complex interaction between the cervix, fetal membrane, and uterine contractions before the onset of labor was analyzed, more specifically, the impact of the following physiological conditions on the maximum principal stress distribution, cervical remodeling in terms of shape change, and fetal membrane rupture: (i) initial cervical shape, (ii) cervical stiffness, (iii) cervical contractions, and_(iv) intrauterine pressure. In this work, a multilayer fetal membrane model was developed, comprising the . . .
  

   

  

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