Preparation and application of chikungunya pseudovirus containing double reporter genes

HIGHLIGHTS

  • who: Chunyan Su from the Institut have published the research: Preparation and application of chikungunya pseudovirus containing double reporter genes, in the Journal: Scientific Reports Scientific Reports of 30/Nov/2021
  • what: The results of this study demonstrate that CHIKV PsV containing double reporters were successfully produced.
  • how: These results indicated that the recombinant plasmid expressing CHIKV envelope proteins (pMD2.G-CHIKV-env) was successfully constructed as designated (Fig 1c). The results showed that CHIKV PsV could transduce and release the reporter ZsGreen1 into 293T_cells (Fig 3a). As compared with the neutralization activity . . .

     

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