Preparation and in vitro characterization of lactococcus lactis-loaded alginate particles as a promising delivery tool for periodontal probiotic therapy

HIGHLIGHTS

• What: The aim of this present in_vitro study was to develop a carrier system for probiotic bacteria with further goals and attributes of_(I) easy applicability, (II) stable bacterial release and_(III) slow-release kinetics for the bacterial load. The authors focused on alginate-based particles for such a system as it would ensure a long-acting therapeutic medication in the periodontal pocket. In accordance with previous reports , the study demonstrated that the cannula diameter (27 G vs. 20 G) had the most significant influence on the particle radius. The authors examined several settings of stirring rates . . .
  

   

  

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