Preparation and optimization of surface stabilized cryptotanshinone nanocrystals with enhanced bioavailability

HIGHLIGHTS

  • who: COPYRIGHT and colleagues from the Chinese Academy of Medical and Peking Union Medical College, China Gifu University of Medical Science, Japan have published the paper: Preparation and optimization of surface stabilized cryptotanshinone nanocrystals with enhanced bioavailability, in the Journal: (JOURNAL)
  • what: CTS nanocrystals were successfully fabricated by an antisolvent precipitation-homogenization approach with a stabilizer of Poloxamer 407.
  • how: The result indicated that nanocrystals are a suitable delivery approach for CTS oral administration. These results indicated that CTS nanocrystals had a higher absorption rate and improved bioavailability than raw CTS.
 

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