Preparation, characterization and evaluation of prasugrel

HIGHLIGHTS

  • who: USER from the Teresa College of Pharmacy, Hyderabad, Telangana, India have published the paper: Preparation, Characterization and Evaluation of Prasugrel, in the Journal: (JOURNAL)
  • what: The aim of this study was to investigate nanosuspensions for enhancing the solubility and dissolution rate of Prasugrel HCl (PHCl) so as to reduce the fluctuations in its oral bioavailability.
  • how: Establishment of an in-vitro dissolution test as a surrogate for animal testing/human studies was explored in this study to support PHCl nanosuspension formulation development. The smallest size nanosuspension was used in the study.
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