Pressure reveals unique conformational features in prion protein fibril diversity

HIGHLIGHTS

• who: Protein Fibril Diversity et al. from the Institut National de la Recherche Agronomique, UR892, Virologie Immunologie Moléculaires, Jouy-enJosas, France Sorbonne Universités, UPMC Univ Paris, CNRS, UMR8233, MONARIS, Université Pierre et Marie have published the article: Pressure Reveals Unique Conformational Features in Prion Protein Fibril Diversity, in the Journal: Scientific Reports Scientific Reports of 10/01/2019
• what: The authors show that pressure induces dissociation of the fibrils albeit with different kinetics. The authors propose that the structural of PrP fibrils encompass a multiplicity of packing defects (water-excluded cavities) in their . . .
  

   

  

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