Prevalence of alternative lengthening of telomeres in pediatric sarcomas determined by the telomeric dna c-circle assay

HIGHLIGHTS

  • What: The authors investigate the frequency of ALT in Ewing`s family sarcoma (EFS), rhabdomyosarcoma (RMS), and osteosarcoma (OS) by analyzing DNA from fresh frozen primary tumor samples utilizing the real-time PCR C-circle Assay (CCA).
  • Who: Jeremy Wang et al. from the University of North Carolina at Chapel Hill, United States have published the research work: Prevalence of alternative lengthening of telomeres in pediatric sarcomas determined by the telomeric DNA C-circle assay, in the Journal: (JOURNAL) of 11/03/2024
  • How: Although there is no standardized method for determining ALT . . .

     

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