HIGHLIGHTS
- who: Anita Kruzik from the Innovations GmbH, a member of the Takeda group of companies, Vienna, Austria have published the Article: Prevalence of Anti-Adeno-Associated Virus Immune Responses in International Cohorts of Healthy Donors, in the Journal: (JOURNAL) of 14/09/2019
- what: The authors report higher than expected NAb prevalence, which was supported by correlating IgG levels but did not correlate with anti-AAV T_cell responses detectable in the circulation.
SUMMARY
Even low titers of NAbs against AAV8 have been shown to block in_vivo transduction, and CD8 T_cells specific . . .
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