Prevalence of igfbp3, nos3 and tcf7l2 polymorphisms and their association with hypertension: a population-based study with brazilian women of african descent

HIGHLIGHTS

• who: Abel Barbosa Lira Neto from the , is a protein with the function of regulating the bioavailability of , [6]In vitro experiments indicate that , regulates , by reducing vascular resistance when stimulating the synthesis of NO in endothelial cells [7]. Therefore, serum levels are closely related to the production of endothelial NO and, consequently, to oxidative stress and hypertension [8]. Sedentary lifestyle, visceral adiposity, and insulin resistance are important risk factors for both hypertension and diabetes mellitus (DM). However, although several studies have demonstrated a relationship between the TCF , gene and DM, its relationship with the prevalence of . . .
  

   

  

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