Prevention of anti-hmgcr immune-mediated necrotising myopathy by c5 complement inhibition in a humanised mouse model

HIGHLIGHTS

• who: Sarah Julien and collaborators from the INSERM, PAn`THER FOCIS Center of Excellence, Universitu00e9 de Rouen, Rouen, France Department of Internal Medicine and Clinical Immunology, Pitiu00e9-Salpu00eatriu00e8re University Hospital have published the article: Prevention of Anti-HMGCR Immune-Mediated Necrotising Myopathy by C5 Complement Inhibition in a Humanised Mouse Model, in the Journal: Biomedicines 2022, 10, x FOR PEER REVIEW of 21/07/2022
• what: The aim of this study was to pre-clinically evaluate the C5 inhibitor zilucoplan in a humanized mouse model of IMNM and to compare its efficacy when used in . . .
  

   

  

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