HIGHLIGHTS
- who: Michael J. Diaz et al. from the CollegeUniversity of Florida, Gainesville, FL, USA have published the article: Primary and Metastatic Cutaneous Melanomas Discriminately Enrich Several Ligand-Receptor Interactions, in the Journal: Life 2023, 13, 180. of /2023/
- what: Since the manifestation and development of CM encompass mutual regulation by gene_expression and the immune microenvironment, this study aims to elucidate the ligand-receptor signaling architecture in both primary tumors and metastasis from previously published bulk gene_expression data. In the study , RSPO1 and RSPO3 were identified as important stroma-to-tumor ligands, each interacting with both . . .
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