Priming of colorectal tumor-associated fibroblasts with zoledronic acid conjugated to the anti-epidermal growth factor receptor antibody cetuximab elicits anti-tumorv2 t lymphocytes

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  • who: Jordi Leonardo Castrillo Fernandez and collaborators from the Molecular Oncology and Angiogenesis Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy Department of Experimental Medicine, University of Genoa, Genoa, Italy have published the Article: Priming of Colorectal Tumor-Associated Fibroblasts with Zoledronic Acid Conjugated to the Anti-Epidermal Growth Factor Receptor Antibody Cetuximab Elicits Anti-TumorV2 T Lymphocytes, in the Journal: Cancers 2023, 610 of 19/Dec/2022
  • what: The authors show that CRC-derived TAF can be turned by zoledronic acid (ZA) in soluble form or as antibody-drug conjugate (ADC) into efficient stimulators . . .

     

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