HIGHLIGHTS
- who: Angu00e9lique Igel from the Universitu00e9 Paris-Saclay, INRAE, UVSQ, VIM, Jouyu2011enu2011Josas, France have published the research work: Prion assemblies: structural heterogeneity, mechanisms of formation, and role in species barrier, in the Journal: (JOURNAL)
- what: In this review, the authors show evidence that u00adPrPSc assemblies are structurally heterogeneous. In the second part of the review, the authors will elaborate on the mechanisms of u00adPrPSc diversification.
SUMMARY
The quantitative aspects of prion accumulation (PrPSc levels or infectivity) during neuroinvasion have served to elaborate prion replication models. At the strain level, this corresponds . . .
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