Prion protein expression regulates embryonic stem cell pluripotency and differentiation

HIGHLIGHTS

  • who: Pluripotency and collaborators from the Centro de Investigación en Sanidad Animal, Instituto Nacional de Investigación y Tecnologı́a Agraria y Alimentaria, Madrid, Spain have published the research work: Prion Protein Expression Regulates Embryonic Stem Cell Pluripotency and Differentiation, in the Journal: (JOURNAL) of November/23,/2010
  • what: This study examines the functionality of PRNP during the course of embryoid body (EB) in mouse Prnp-null (KO) and WT embryonic stem cell (ESC) lines. The authors here present the first evidence that Prnp is involved in regulating the self-renewal/differentiation status of . . .

     

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