Probc: joint modeling of epigenome and transcriptome effects in 3d genome

HIGHLIGHTS

  • who: Emre Sefer from the (UNIVERSITY) have published the research: ProbC: joint modeling of epigenome and transcriptome effects in 3D genome, in the Journal: (JOURNAL)
  • what: The authors focus on the problem of identifying the relationships between high-order chromatin interactions and chromatin marks; epigenetic and transcriptionrelated marks. Distinctively, the authors aim to understand and predict how Hi-C and Micro-C interactions are formed as a result of these marks and interactions within them. The authors propose a generative probabilistic method PROBC to decompose genome-wide Hi-C and Micro-C interactions by chromatin . . .

     

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