Probdnf and its receptors in immune-mediated in diseases: novel insights into the regulation of metabolism and mitochondria

HIGHLIGHTS

  • who: April and collaborators from the University of Virginia, United States have published the Article: ProBDNF and its receptors in immune-mediated in diseases: novel insights into the regulation of metabolism and mitochondria, in the Journal: (JOURNAL)
  • what: In this review, the potential effects of proBDNF and its receptors on glucose, lipid, and mitochondrial metabolism in IMIDs were explored and concluded. The authors focused on the p75NTR target and prepared p75ECD from prokaryotic and eukaryotic cells.
  • future: P75NTR serves as a neurotrophin receptor thus future studies must be conducted to determine whether or . . .

     

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