HIGHLIGHTS
- who: ufeffYunufeff ufeffDaiufeff and colleagues from the Departments of Gastroenterology, Peking University First Hospital, Beijing, China have published the research work: Probiotic ufeffEscherichia coliufeff Nissle 1917 Expressing Elafin Protects Against Inflammation and Restores the Gut Microbiota, in the Journal: (JOURNAL)
- what: The authors aimed to construct Elafin-expressing EcN and determine its therapeutic effects on experimental colitis, with a particular focus on its impact on the intestinal epithelial barrier function and microbiota composition. The authors show here EcN-Elafin administration restricts paracellular permeability by regulating the expression and distribution of tight junction protein ZO-1 . . .
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