Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying european gmp

HIGHLIGHTS

  • who: Moyra Lawrence from the (UNIVERSITY) have published the article: Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying European GMP, in the Journal: (JOURNAL) of 10/02/2021
  • what: This analysis has also provided the authors with an estimation of the cost of each manufacturing batch, as well as important considerations for scaling up and automation.
  • how: As a result of process and FMEA analyses the following additions were designed 1) QC control points should be introduced early in the MK differentiation process to identify failing cultures before . . .

     

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