Production of fully active recombinant murine granzyme b in yeast*

HIGHLIGHTS

  • who: Christine T.N. Pham from the (UNIVERSITY) have published the Article: Production of Fully Active Recombinant Murine Granzyme B in Yeast*, in the Journal: (JOURNAL) of September/26,/1997

SUMMARY

    The authors expressed the proenzyme form of GzmB as well and determined that pro-GzmB is efficiently converted to its active form by the cysteine proteinase dipeptidyl peptidase I. Although the enzymes responsible for the activation of these caspases are unknown, there is evidence that these enzymes can autoactivate or cross-activate other family members. Previous studies could not determine whether the . . .

     

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