Profiling of fatty acid metabolism in the dorsal root ganglion after peripheral nerve injury

HIGHLIGHTS

• who: Shota Yamamoto and Hideo Shindou from the University of Porto, Portugal United States have published the Article: Profiling of fatty acid metabolism in the dorsal root ganglion after peripheral nerve injury, in the Journal: (JOURNAL)
• what: In this study, although AEA levels were not altered, PNI increased the amount of OEA, which was reported to activate peroxisome proliferator-activated receptor-u03b1 (PPARu03b1), with a median effective concentration of 0.12 u00b5M . Given that most of FAs are stored as glycerophospholipids, the studies focused on glycerophospholipids will be needed to understand PNI pathologies.
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