HIGHLIGHTS
- who: David Stahl and colleagues from the Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany have published the research: Prognostic Gene Expression, Stemness and Immune Microenvironment in Pediatric Tumors, in the Journal: Cancers 2021, 13, 854. of 30/09/2019
- what: The authors focused on macrophages enumerated by CIBERSORT, because of their high abundance and easy detection and quantification by immunhistochemistry in situ. The authors demonstrate a correlation of stemness with precursor cell morphology, molecular and clinical subtype, but not with a distinct pattern of the immune TME defined by CIBERSORT.
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