Prognostic implication of heterogeneity and trajectory progression induced by enzalutamide in prostate cancer

HIGHLIGHTS

  • who: Yuanfa Feng from the Peking People`s Hospital, China have published the paper: Prognostic implication of heterogeneity and trajectory progression induced by enzalutamide in prostate cancer, in the Journal: (JOURNAL)
  • what: The authors explored the cell heterogeneity and transcriptional alteration that induced by enzalutamide and identified a heterogeneous cluster that resists enzalutamidetreatment by using single-cell_RNA_sequencing (scRNA-seq) analysis. Differential expression analysis was carried out to explore the DEGs between C7 and other clusters.
  • how: Standard pre-processing workflow including data normalization and scaling and the detection of highly variable features were . . .

     

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