HIGHLIGHTS
SUMMARY
Patients from other hospitals were used for external validation, including 316 stroke patients within 4.5 h of onset (control group) and 114 patients with wake-up stroke (WUS group). The prediction of neurological outcomes in ischemic stroke patients is very useful in treatment choices, as well as in poststroke management (Jiang et_al, 2021; Kerleroux et_al, 2021). Independent prognostic factors in the primary cohort Validation of predictive accuracy of the logistic model for outcome severity Unfavorable outcomes (mRs > 1) were observed in 114 (23.4%) of the 488 patients in the in-house dataset . . .

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