Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive her2 + breast carcinoma

HIGHLIGHTS

  • who: Charles N. Birts from the School University of have published the research: Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma, in the Journal: Scientific Reports Scientific Reports
  • what: The subsequent analysis focused on B-CLS. The mechanism of CLS formation has been extensively reviewed ­elsewhere7,8, thus in this exploratory study, the authors focused the investigation into the phenotype and prognostic role of CLS in 188 patients with HER2 + primary breast cancer.
  • how: This study was conducted in a retrospective series of 188 . . .

     

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