HIGHLIGHTS
- who: Charles N. Birts from the School University of have published the research: Prognostic significance of crown-like structures to trastuzumab response in patients with primary invasive HER2 + breast carcinoma, in the Journal: Scientific Reports Scientific Reports
- what: The subsequent analysis focused on B-CLS. The mechanism of CLS formation has been extensively reviewed elsewhere7,8, thus in this exploratory study, the authors focused the investigation into the phenotype and prognostic role of CLS in 188 patients with HER2 + primary breast cancer.
- how: This study was conducted in a retrospective series of 188 . . .
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