Progression induced by lysine 280-acetylated tau in cell and mouse models

HIGHLIGHTS

• who: Monoclonal antibody Y and collaborators from the ADEL InstituteYonsei University have published the paper: progression induced by lysine 280-acetylated tau in cell and mouse models, in the Journal: (JOURNAL)
• what: The authors demonstrate that tau-acK280 is critical for tau propagation processes including secretion aggregation and seeding. The authors performed extensive investigations to show that tau acetylation at K280 is essential for propagation of tauopathy, leading to progression of irreversible neurodegenerative diseases such as AD.
• how: Information on the sexes of mice used in the study is summarized in Supplemental Table . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.