HIGHLIGHTS
- who: Prohibitins A Key Link and collaborators from the School of Medicine, Yangzhou University, Yangzhou, China have published the research: Prohibitins: A Key Link between Mitochondria and Nervous System Diseases, in the Journal: Oxidative Medicine and Cellular Longevity 7 of 21/06/2022
- what: In this review, we have shown the critical roles played by PHBs in the regulation of mitochondria, transcription, and cellular aging.
SUMMARY
Silencing of PHB in intestinal epithelial_cells activates mitochondrial stress-related autophagy, by increasing reactive oxygen species (ROS) levels. Overexpression of PHB resulted in decreased sensitivity . . .
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