Proinflammatory plasticity towards th17 paradigm of regulatory t cells consistent with elevated prevalence of

HIGHLIGHTS

• who: Jingjing Cao from the (UNIVERSITY) have published the research work: Proinflammatory plasticity towards Th17 paradigm of regulatory T cells consistent with elevated prevalence of, in the Journal: (JOURNAL)
• what: Primary ITP demonstrated skewed Treg plasticity towards Th17 paradigm, which was further aggravated in elderly patients presenting ITP since their 6th decade of age.
• future: The observation might be among the early evidences indicating the role of Treg senescence in the pathogenesis of primary ITP although further investigations are required to illustrate the association between T_cell senescence markers and the extent of Treg . . .
  

   

  

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