Proinsulin-reactive cd4 t cells in the islets of type diabetes organ donors

HIGHLIGHTS

  • who: Laurie G. Landry and colleagues from the Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO, United States have published the research work: Proinsulin-Reactive CD4 T Cells in the Islets of Type Diabetes Organ Donors, in the Journal: (JOURNAL)
  • what: The authors report the molecular elements involved in the immune-recognition of preproinsulin peptides by islet-derived CD4 T_cells. cells reactive to beta cell antigens are present in the islets of organ donors having T1D . The authors aimed to comprehensively analyze and characterize tri-molecular complexes composed of . . .

     

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