Prokineticin receptor-1 signaling promotes epicardial to mesenchymal transition during heart development

HIGHLIGHTS

  • who: Himanshu Arora from the CNRS de Strasbourg, UMR7242, Ecole SupĂ©rieure de Biotechnologie de Strasbourg, Illkirch, France have published the article: Prokineticin receptor-1 signaling promotes Epicardial to Mesenchymal Transition during heart development, in the Journal: Scientific Reports Scientific Reports
  • what: The authors provide evidence for the critical role of epicardial-PKR1 signaling in cardiac development, and how defective epicardial signaling manifests in forms of congenital heart diseases in adult heart, focusing on the EMT programming process (Fig 7).

SUMMARY

    Verification of loss of PKR1 in heart of mutant lines . . .

     

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