Prolactin receptor signaling: a novel target for cancer treatment – exploring anti-prlr signaling strategies

HIGHLIGHTS

  • who: David Standing and colleagues from the Malades, France Washington University in StLouis have published the article: Prolactin receptor signaling: A novel target for cancer treatment - Exploring anti-PRLR signaling strategies, in the Journal: (JOURNAL)
  • what: The authors demonstrate that Penfluridol binds to the PRLR ICD, and potently inhibits PRL: PRLR signaling that results in the inhibition of PDAC growth.
  • future: Antibody based therapies may have significant potential for use in the future though further study and designs are required to fully assess their prospective use.

SUMMARY

    In preclinical . . .

     

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