Prolonged b-lymphocyte-mediated immune and inflammatory responses to tuberculosis infection in the lungs of tb-resistant mice

HIGHLIGHTS

• who: Irina Linge and collaborators from the Laboratory for Immunogenetics, Central Tuberculosis Research Institute, Moscow, Russia have published the article: Prolonged B-Lymphocyte-Mediated Immune and Inflammatory Responses to Tuberculosis Infection in the Lungs of TB-Resistant Mice, in the Journal: (JOURNAL)
• what: The authors demonstrate that cells and BCFs persist up to weeks B-cell content markedly drops between weeks 12-16 post-infection paralleled by diffuse lung tissue inflammation and elevated gene expression levels for cytokines IL-1 IL-11 IL-17a and TNF-u03b1. The authors first compared B-cell migration and . . .
  

   

  

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