Prolonged fos activity disrupts a global myogenic transcriptional program by altering 3d chromatin architecture in primary muscle progenitor cells

HIGHLIGHTS

• who: A. Rasim Barutcu from the Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA have published the research: Prolonged FOS activity disrupts a global myogenic transcriptional program by altering 3D chromatin architecture in primary muscle progenitor cells, in the Journal: (JOURNAL)
• what: The authors established a lentiviral, doxycyclineinducible system to explore the effects of persistent FOS activity on primary muscle progenitor cell fate decisions. While it was recently shown that transient FOS activity in early-activated SCs is crucial for eliciting an effective muscle regenerative response , the . . .
  

   

  

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