Prolonged inhibition of class i pi3k promotes liver cancer stem cell expansion by augmenting sgk3/gsk-3β/β-catenin signalling

HIGHLIGHTS

• who: Fengchao Liu from the The Huh, cells were obtained from the Chinese Academy of Sciences Cell BankThe MHCC- H cells were obtained from Zhongshan Hospital of Fudan University in Shanghai, China. All cells were maintained in Dulbecco's modified Eagle medium (DMEM have published the research work: Prolonged inhibition of class I PI3K promotes liver cancer stem cell expansion by augmenting SGK3/GSK-3β/β-catenin signalling, in the Journal: (JOURNAL)
• what: The authors show that SGK3 is preferentially activated in liver CSCs, and upregulated or downregulated SGK3 in HCC cells enhances or suppresses liver . . .
  

   

  

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