Properties and potential antiproliferative activity of thrombin-binding aptamer (tba) derivatives with one or two additional g-tetrads

HIGHLIGHTS

  • who: Daniela Benigno et al. from the Department of Pharmacy, University of Naples Federico II, Napoli, Italy have published the research: Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads, in the Journal: (JOURNAL) of 29/Nov/2022
  • what: For these reasons, a significant part of the research focused on the antiproliferative activity of TBA has been addressed with 2 of 12 chemical modifications aimed at increasing thermal and biological resistance and weakening the anticoagulant activity without affecting the antiproliferative one.
  • how: The antiproliferative . . .

     

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