Prophylactic administration of mir-451 inhibitor decreases osteoarthritis severity in rats

HIGHLIGHTS

• who: Kayla M. Scott from the CollegeCommonwealth University have published the paper: Prophylactic administration of miR-451 inhibitor decreases osteoarthritis severity in rats, in the Journal: Scientific Reports Scientific Reports
• what: The research has shown that miR-451 is specifically increased in OA articular cartilage, although in_vitro studies indicate that it does not induce apoptosis or compromise cell viability in u00adchondrocytes9,23.
• how: All animal studies were conducted in accordance with ARRIVE guidelines.

SUMMARY

For each study (prophylactic v. therapeutic), 9 rats were treated with miR-451 power inhibitor . . .

 



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