HIGHLIGHTS
- who: Chuanchang Li and Yongping Bai from the Asahikawa Medical University, Japan have published the research: Prophylactic exercise-derived circulating exosomal MiR-125a-5p promotes endogenous revascularization after hindlimb ischemia by targeting endothelin converting enzyme 1, in the Journal: (JOURNAL)
- what: Among them, the authors focused on miR-125a-5p, the most abundant miRNA in plasma-derived exosomes released by exercise or sedentary rats (Supplementary Table 1). The authors report on the exciting new observation that endogenous circulating exosomal miR-125a-5p is a novel exerkine promoting precursory exercise-induced arteriogenesis, angiogenesis and perfusion recovery . . .
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